
Global蛋白Sumoylation Assay试剂盒(ab115131)
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产品名称 | Global蛋白Sumoylation Assay试剂盒 |
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品牌 | 艾博抗Abcam |
货号 | ab115131 |
样品类型 | Cell culture extracts, Tissue Extracts |
检测时间 | 5h 00m |
种属反应性 | 与反应: Mouse, Rat, Human 预测可用于: Mammals |
产品概述 | Sumoylation is a post-transcriptional modification involved in various cellular processes such as nuclear-cytoplasmic transport, transcription regulation and progression through the cell cycle. There are 3 confirmed SUMO isoforms in humans: SUMO-1, SUMO-2 and SUMO-3. SUMO-2/-3 show a high degree of similarity to each other and are distinct from SUMO-1. Sumoylation is directed by an enzymatic cascade analogous to that involved in ubiquitination. Sumoylation of target proteins in vivo has been shown to cause a number of different outcomes, including altered localization and binding partners. Thus, detection of in vivo protein sumoylation (SUMO conjugation) would provide useful information for understanding SUMO modification as a regulatory control mechanisms for many nuclear proteins.Global Protein Sumoylation Assay Kit (ab115131) allows the user to measure in vivo protein sumoylation. The kit is ready-to-use and provides all the essential components needed for measuring in vivo protein sumoylation from multiple mammalian cells/tissues extracts. |
研究领域 | Epigenetics and Nuclear Signaling Chromatin Modifying Enzymes Sumoylation Kits/ Lysates/ Other Kits Epigenetic kits Sumoylation Epigenetics and Nuclear Signaling Assays & Kits Sumoylation |
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