Anti-ABCC1 Antibody,500 ug/ml
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| 货号 | M00872 |
|---|---|
| 产品名称 | Anti-ABCC1 Antibody |
| 基因名 | ABCC1 |
| 抗体来源 | Mouse |
| 克隆 | Monoclonal |
| 抗体亚型 | Mouse |
| 免疫原 | Recombinant human full-length ABCC1 |
| 内容 | Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| 浓度 | 500 ug/ml |
| 产品形态 | Liquid |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing. |
| 背景资料 | Multidrug resistance-associated protein 1 (MRP1) is a protein that in humans is encoded by the ABCC1 gene. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. |
| 研究类别 | 1. "Entrez Gene: ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1".2. Rosenberg MF, Mao Q, Holzenburg A, Ford RC, Deeley RG, Cole SP (May 2001). "The structure of the multidrug resistance protein 1 (MRP1/ABCC1). crystallization and single-particle analysis". The Journal of Biological Chemistry. 276 (19): 16076–82.3. Yin J, Zhang J (October 2011). "Multidrug resistance-associated protein 1 (MRP1/ABCC1) polymorphism: from discovery to clinical application". Zhong Nan Da Xue Xue Bao. Yi Xue Ban = Journal of Central South University. Medical Sciences. 36 (10): 927–38. |
| Uniprot ID | ABCC1: |
| 检验物种 | human |
| 产品类型 | Monoclonal |
| 应用范围 | IHC |
| 发货周期 | 3-4周 |
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