
人 ADAM15 (NM_001261465) cDNA克隆
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商品名称 | 人 ADAM15 (NM_001261465) cDNA克隆 |
---|---|
品牌 | 丰晖生物 |
货号 | G113773 |
accession | NM_001261465 |
基因别名 | ADAM15 |
基因描述 | Homo sapiens ADAM metallopeptidase domain 15 (ADAM15), transcript variant 8, mRNA. |
载体 | pDONR223 |
CDS区长度 | 2391 |
翻译后氨基酸长度 | 796 |
TranscriptVariant | This variant (8) lacks two alternate in-frame exons in the 3' coding region compared to variant 6. The resulting protein (isoform 8) is shorter compared to isoform 6. |
基因简介 | The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] |
规格 | 10ul 质粒 |
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